Article

SCALLOPS: a scalable, integrated computational framework for Optical Pooled Screens

Optical pooled screens (OPS) link pooled genetic perturbations to high-dimensional image-based phenotypes at scale, but their widespread adoption is hindered by computational …

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Joshua Gould

Linking live-cell behavior to transcriptional responses across perturbations using dynamic caging

Single-cell technologies, encompassing molecular, morphological, and functional assays, have emerged as cornerstones of modern biological research and discovery. However, current …

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Brian Orcutt-Jahns
An example preprint / working paper featured image

An example preprint / working paper

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Dr. Alex Johnson

STAR-Fusion: Fast and Accurate Fusion Transcript Detection from RNA-Seq

**Motivation:** Fusion genes created by genomic rearrangements can be potent drivers of tumorigenesis. However, accurate identification of functionally fusion genes from genomic …

B. haas