DETONATE
DETONATE (DE novo TranscriptOme rNa-seq Assembly with or without the Truth Evaluation) is a de novo transcriptome assembly evaluation package, which contains two components, RSEM-EVAL and REF-EVAL. Bo developed the RSEM-EVAL component.
Authors
Principal Scientist II
Dr. Bo Li is a Principal Scientist at Genentech, Inc. His research focuses on large-scale single-cell genomics data analysis.
Before joining in Genentech, he was an Assistant Professor of Medicine at Harvard Medical School and the director of Bioinformatics and Computational Biology at Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital.
He received his Ph.D. in computer science from UW-Madison and completed two postdoctoral trainings with Dr. Lior Pachter at UC Berkeley and Dr. Aviv Regev at Broad Institute.
He is best known for developing RSEM, an impactful RNA-seq transcript quantification software. RSEM is cited 22,602 times (Google Scholar) and adopted by several big consortia such as TCGA, ENCODE, GTEx and TOPMed.
Authors