RSEM (RNA-Seq by Expectation-Maximization)
RSEM is a widely-used RNA-Seq transcript quantification tool. RSEM papers are cited over 5,300 times. It was served in nationwide consortium projects such as ENCODE (The Encyclopedia of DNA Elements) and TCGA (The Cancer Genome Altas). It is also recommended by HCA (Human Cell Atlas) for analyzing plate-based SMART-Seq2 single-cell RNA-Seq data.
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